Seung Woo Cho, PhD
Entire publications of PI are available through the following links.
Publications
Carter, Ava C.; Xu, Jin; Nakamoto, Meagan Y., et al. Spen links RNA-mediated endogenous retrovirus silencing and X chromosome inactivation. eLife, 2020;9:e54508
Lee, HoJoon; Chang, Howard Y; Cho, Seung Woo, et al. CRISPRpic: fast and precise analysis for CRISPR-induced mutations via prefixed index counting. NAR Genomics and Bioinformatics, Volume 2, Issue 2, June 2020
Rubin, Adam J.; Parker, Kevin R.; Satpathy, Ansuman T., et al. Coupled Single-Cell CRISPR Screening and Epigenomic Profiling Reveals Causal Gene Regulatory Networks. Cell, Volume 176, Issues 1–2, 10 January 2019, Pages 361-376.e17
Corces, M. Ryan; Granja, Jeffrey M.; Shams, Shadi, et al. The chromatin accessibility landscape of primary human cancers. Science, 26 Oct 2018
Cho, Seung Woo; Xu, Jin; Sun, Ruping, et al. Promoter of lncRNA Gene PVT1 Is a Tumor-Suppressor DNA Boundary Element. Cell, Volume 173, Issue 6, 31 May 2018, Pages 1318-1319
Mumbach, Maxwell R.; Satpathy, Ansuman T.; Boyle, Evan A., et al. Enhancer connectome in primary human cells identifies target genes of disease-associated DNA elements. Nat Genet, 49, 1602–1612 (2017).
Corces, M. Ryan; Trevino, Alexandro E.; Hamilton, Emily G., et al. An improved ATAC-seq protocol reduces background and enables interrogation of frozen tissues. Nat Methods, 14, 959–962 (2017).
Liu, S. John; Horlbeck, Max A.; Cho, Seung Woo, et al. CRISPRi-based genome-scale identification of functional long noncoding RNA loci in human cells. Science, 06 Jan 2017
Chen, Xingqi; Shen, Ying; Draper, Will, et al. ATAC-see reveals the accessible genome by transposase-mediated imaging and sequencing. Nat Methods, 13, 1013–1020 (2016).
Woo, Je Wook; Kim, Jungeun; Il Kwon, Soon, et al. DNA-free genome editing in plants with preassembled CRISPR-Cas9 ribonucleoproteins. Nat Biotechnol, 33, 1162–1164 (2015).
Hyun, Youbong; Kim, Jungeun; Cho, Seung Woo, et al. Site-directed mutagenesis in Arabidopsis thaliana using dividing tissue-targeted RGEN of the CRISPR/Cas system to generate heritable null alleles. Planta 241, 271–284 (2015).
Cho, Seung Woo; Chang, Howard Y. CRISPR engineering turns on genes. Nature 517, 560–562 (2015).
Kim, Sojung; Kim, Daesik; Cho, Seung Woo, et al. Highly efficient RNA-guided genome editing in human cells via delivery of purified Cas9 ribonucleoproteins. Genome Res, 2014. 24: 1012-1019
Ramakrishna, Suresh; Cho, Seung Woo; Kim, Sojung, et al. Surrogate reporter-based enrichment of cells containing RNA-guided Cas9 nuclease-induced mutations. Nat Commun, 5, 3378 (2014).
Cho, Seung Woo; Kim, Sojung; Kim, Yongsub, et al. Analysis of off-target effects of CRISPR/Cas-derived RNA-guided endonucleases and nickases. Genome Res. 2014. 24: 132-141
Cho, Seung Woo; Lee, Jihyun; Carroll, Dana, et al. Heritable Gene Knockout in Caenorhabditis elegans by Direct Injection of Cas9-sgRNA Ribonucleoproteins. GENETICS November 1, 2013 vol. 195 no. 3 1177-1180
Cho, Seung Woo; Kim, Sojung; Kim, Jong Min, et al. Targeted genome engineering in human cells with the Cas9 RNA-guided endonuclease. Nat Biotechnol 31, 230–232 (2013).
Kim, Hye Joo; Lee, Hyung Joo; Kim, Hyojin, et al. Targeted genome editing in human cells with zinc finger nucleases constructed via modular assembly. Genome Res. 2009. 19: 1279-1288